Abstract -- Emergency physicians often encounter poisoned patients exposed to agents, intentionally or
unintensionally, with known or unknown nature. The exposure may be iatrogenic (drugs interaction)
or non-iatrogenic. The scenarios range from industrial disaster, occupational exposure, recreational
mishap, natural catastrophe, chemical warfare, and acts of terrorism. We review papers of toxidromes
regarding to clinical presentation, physical examination findings, and laboratory finding to aid
emergency physicians differentiating commonly encounterd poisons. Nevertheless, evidence-based
approaches and clinical trials are limited. Current management is mostly based on expert-consensus
from previous tragic experiences. In this review article, current accepted management for common
poisonings also are introduced.